Amide
DEFINITIONS
Each one of the members of two classes that contain nitrogen in senyawaorganik, always contains a carbonyl group (-C = O). The first class, amide kovalendibentuk by replacing the hydroxyl group (-OH) of the amino acid group (-NR2, where R may represent a hydrogen atom or an organic combining group such as methyl). Amide formed from carboxylic acids, called
carboxamides
, Is padatankecuali for the most simple, is in the form of liquid formamide. Amide does not conduct electricity, has a high boiling point, and (when liquid) is a solvent that baik.Tidak no natural sources of simple covalent amide practical, but the peptide and proteindalam living systems is a long chain (polymer) with a peptide bond. Adalahsuatu urea amides with two amino groups. Commercial amides, including some kovalendigunakan as solvent, while the other is a sulfa drug and nylon. The second class, the amide ions (such as salt), prepared by treating a covalent amide, amine atauamonia with reactive metals (eg sodium) and alkaline kuat.Sebuah derivatives of carboxylic acids with RCONH2
DEFINITIONS
Each one of the members of two classes that contain nitrogen in senyawaorganik, always contains a carbonyl group (-C = O). The first class, amide kovalendibentuk by replacing the hydroxyl group (-OH) of the amino acid group (-NR2, where R may represent a hydrogen atom or an organic combining group such as methyl). Amide formed from carboxylic acids, called
carboxamides
, Is padatankecuali for the most simple, is in the form of liquid formamide. Amide does not conduct electricity, has a high boiling point, and (when liquid) is a solvent that baik.Tidak no natural sources of simple covalent amide practical, but the peptide and proteindalam living systems is a long chain (polymer) with a peptide bond. Adalahsuatu urea amides with two amino groups. Commercial amides, including some kovalendigunakan as solvent, while the other is a sulfa drug and nylon. The second class, the amide ions (such as salt), prepared by treating a covalent amide, amine atauamonia with reactive metals (eg sodium) and alkaline kuat.Sebuah derivatives of carboxylic acids with RCONH2
as a general formula, where Radalah hydrogen or alkyl or aryl radical. Amida is divided into several sub-classes, depending on the number of substituents on the nitrogen. Simple or primary, that is amidadibentuk by replacing the carboxylic hydroxyl group by an amino group, NH2
. Inidiberi compound name by dropping acid "-ic" or "-OIC" from the name origin danmenggantinya carboxylic acid with the suffix 'amide'. In secondary and tertiary amides, one ataukedua hydrogen is replaced by other groups. The presence of the prefix tersebutditunjuk group N (for nitrogen). Except for formamide, all the simple amides is melted solid, stable, danasam weak. They are strongly associated through hydrogen bonding, so soluble in the solvent
hydroxylic
, Such as water and alcohol. Because of the ease of formation and a sharp melting point, amides are often used for identification of organic acids and amines identification. Persiapankomersial amide involves thermal dehydration of the carboxylic acid ammonium salt.
